Infinite Loops

My guest today is Michael Garfield, a paleontologist, futurist, writer, podcast host and strategic advisor whose “mind-jazz” performances — essays, music and fine art — bridge the worlds of art, science and philosophy. This year, Michael received a $10k O’Shaughnessy Grant for his “Humans On the Loop” discussion series, which explores the nature of agency, power, responsibility and wisdom in the age of automation. This whirlwind discussion is impossible to sum up in a couple of sentences (just look at the number of books & articles mentioned!) Ultimately, it is a conversation about a subject I think about every day: how we can live curious, collaborative and fulfilling lives in our deeply weird, complex, probabilistic world. I hope you enjoy this conversation as much as I did. For the full transcript, episode takeaways, and bucketloads of other goodies designed to make you go, “Hmm, that’s interesting!”, check out our Substack. Important Links: Michael’s Website Humans On The Loop Twitter Future Fossils Substack Show Notes: What is “mind jazz”? Humans “ON” the loop? The Red Queen hypothesis and the power of weirdness Probabilistic thinking & the perils of optimization Context collapse, pernicious convenience & coordination at scale How organisations learn Michael as World Emperor MORE! Books, Articles & Podcasts Mentioned: The Nature of Technology: What It Is and How It Evolves; by W. Brian Arthur Pharmako-AI; by K Allado-McDowell The Global Brain: The Evolution of Mass Mind from the Big Bang to the 21st Century; by Howard Bloom The Genius of the Beast: A Radical Re-Vision of Capitalism; by Howard Bloom One Summer: America, 1927; by Bill Bryson Through the Looking-Glass, and What Alice Found There; by Lewis Carroll The Beginning of Infinity: Explanations That Transform the World; by David Deutsch Scale Theory: A Nondisciplinary Inquiry; by Joshua DiCaglio Revenge of the Tipping Point: Overstories, Superspreaders and the Rise of Social Engineering; by Malcolm Gladwell The WEIRDest People in the World: How the West Became Psychologically Peculiar and Particularly Prosperous; by Joseph Henrich Do Conversation: There's No Such Thing as Small Talk; by Robert Poynton Reality Hunger: A Manifesto; by David Shields The Time Falling Bodies Take to Light: Mythology, Sexuality and the Origins of Culture; by William Irwin Thompson The New Inquisition: Irrational Rationalism and the Citadel of Science; by Robert Anton Wilson Designing Neural Media; by K Allado-McDowell Pace Layering: How Complex Systems Learn and Keep Learning; by Steward Brand Losing Humanity: The Case against Killer Robots; by Bonnie Docherty What happens with digital rights management in the real world?; by Cory Doctorow The Evolution of Surveillance Part 1: Burgess Shale to Google Glass; by Michael Garfield An Introduction to Extitutional Theory; by Jessy Kate Schingler 175 - C. Thi Nguyen on The Seductions of Clarity, Weaponized Games, and Agency as Art; Future Fossils with Michael Garfield 🎶⚔️👏🏼 205 - Greg Thomas & Stephanie Lepp on Jazz Leadership & Antagonistic Cooperation; Future Fossils with Michael Garfield 🌏🚜🫀212 - Manfred Laubichler & Geoffrey West on Life In The Anthropocene & Living Inside The Technosphere; Future Fossils with Michael Garfield

My guest today is Max Meyer, the proprietor of Arena Magazine, a new quarterly publication exploring technology, capitalism and civilization. Arena’s aim? To “make it okay to dream in public again.” Max and I discuss why he launched a print magazine in 2024, WTF happened to legacy media, the wisdom of Ratatouille and MUCH more. I hope you enjoy this conversation as much as I did. For the full transcript, episode takeaways, and bucketloads of other goodies designed to make you go, “Hmm, that’s interesting!”, check out our Substack. Important Links: Max’s Twitter Arena Magazine The New Needs Friends The Earthly Miracle of the Grocery Store Robert F. Kennedy announces the death of Martin Luther King, Jr. Show Notes: What is going on with legacy media? Print advertising and the race to the bottom The collapse of trust in the media TikTok brain, news consumption & social media as a steam valve Bailouts & the appeal of the “zero interest fairyland” The wisdom of Ratatouille The decline of Presidential oratory American progress & the population bomb that didn’t go off Failure is a ladder The one rule of capitalism Long haul flights: Where’s our roast turkey? Why is Arena a physical magazine? Max as Emperor of the world MORE! Books & Articles Mentioned: The Beginning of Infinity: Explanations That Transform the World; by David Deutsch The Ultimate Resource; by Julian L. Simon The Population Bomb; by Dr Paul R. Ehrlich The Genius of the Beast: A Radical Re-Vision of Capitalism; by Howard Bloom How United Became an Airline; by Andy Kessler (WSJ) This is Water; by David Foster Wallace line.

Parmita Mishra is a computational biologist and the founder & CEO of Precigenetics, a company aiming to become a rocket to precision medicine. Parmita is deeply knowledgeable about cutting-edge biology, particularly epigenetics — how behavior and environment can affect gene function without altering genetic code. Her passion for advancing our understanding of diseases is inspiring (and contagious: OSV is an investor in Parmita’s company!) In our conversation, Parmita and I discuss everything from the curious case of male baldness to how her parents have saved 50,000 lives.  I hope you enjoy this conversation as much as I did. For the full transcript, highlights, and bucketloads of other goodies designed to make you go, “Hmm, that’s interesting!”, check out our Substack. Important Links: LinkedIn Twitter Website Precigenetics Twitter Preciginetics launch post Show Notes: Explaining epigenetics to a golden retriever The curious case of male pattern baldness How to think about biology: start from first principles & beware binary thinking The lens you look through determines what you see The problem of data collection in biology Why the FDA needs to change its approach Why we still don’t understand the human brain Garry Tan’s advice: “Get an idea. Get a co-founder.” What’s been surprising about foundership? Failure is a ladder Obsession & how Parmita’s parents have saved 50,000 lives The most surprising things about America Parmita as World Empress Books Mentioned: What is Life?; by Erwin Schrodinger I should have loved biology; by James Somers Gödel, Escher, Bach: An Eternal Golden Braid; by Douglas Hofstadter The Hypomanic Edge: The Link Between (A Little) Craziness and (A Lot of) Success in America; by John D. Gartner

Professor Luis Seco is a mathematician, educator, and investor. Among many other titles and achievements, he is the Professor of Mathematics at the University of Toronto, Director of the quant research hub Risklab, Chair of the Centre for Sustainable Development at the Fields Institute, and co-founder of the asset management firm Sigma Analysis & Management Ltd. Got all that?! This one was really fun, and not just because Luis is a fellow quant. We discuss how maths resembles Beethoven’s Fifth Symphony, the future of the ‘metaversity’, the most important lesson Luis gives his students, why investing isn't what it used to be, and much more. I hope you enjoy this conversation as much as I did. For the full transcript, episode takeaways, and bucketloads of other goodies designed to make you go, “Hmm, that’s interesting!”, check out our Substack. Important Links: Website Twitter YouTube Show Notes: What Luis learned from the Beethoven of mathematics “Mathematics is the language computers speak” The role of community in an increasingly confusing world Lifelong education & the voyage to the human brain Why to teach is to be human Timebinding & social media as a steam valve What matters more - content or communication? Math as a social science: quantifying risk in a nonlinear world From paper, to numbers, to images: The changing nature of data Why the future of education lies in decentralization Swarm solutions & why we’re in the century of collaboration Metaversities & the case for bringing your kids to work Why managing money is now based on words, not numbers Luis as Emperor of the World MORE! Books Mentioned: The Hitchhiker's Guide to the Galaxy; by Douglas Adams The Two Cultures; by C.P. Snow Zen and the Art of Motorcycle Maintenance; by Robert M. Pirsig Manhood of Humanity; by Alfred Korzybski How to Win Friends and Influence People; by Dale Carnegie The Myth of 1926: How Much Do We Know About Long-Term Returns on U.S. Stocks?; by Edward F. Mcquarrie