Episode 61: AIP for Hashimoto’s — The Pioneering Abbott Pilot Study & Case Reports
Hashimoto’s thyroiditis is the most common autoimmune disease in the world—and yet many people continue to struggle with fatigue, brain fog, pain, and mood symptoms even when their thyroid labs look “normal.”
In this episode of the Autoimmune Wellness Podcast, Mickey Trescott continues the AIP Medical Research Review series with a deep dive into the very first clinical study ever conducted on the Autoimmune Protocol for Hashimoto’s thyroiditis. This community-supported pilot study, led by Dr. Rob Abbott and published in 2019, examined whether a structured AIP diet and lifestyle intervention could improve quality of life, inflammation, and symptom burden in adults with Hashimoto’s who were already medically stable.
Mickey walks through the full story behind the study—from the chance meeting that sparked the research, to the grassroots crowdfunding effort that made it possible. She breaks down the study design, participant profile, intervention structure, clinical measures, and results, including detailed case reports that offer rare insight into individual experiences.
This episode highlights a critical and often overlooked reality in Hashimoto’s care: meaningful improvements in how people feel and function can occur even when thyroid hormones and antibodies remain largely unchanged.
In this episode, you’ll learn:
How the first AIP study for Hashimoto’s thyroiditis came to be
Why Hashimoto’s patients often struggle despite “normal” thyroid labs
Who participated in the Abbott pilot study and why that matters
What the AIP intervention looked like in a clinical research setting
How diet, nutrient density, and lifestyle practices were integrated
Which clinical measures were used to assess symptoms, inflammation, and quality of life
What the study revealed about fatigue, pain, mood, and daily functioning
Why improvements occurred even though thyroid hormones stayed stable
What happened with thyroid antibodies and systemic inflammation
Why some participants required lower doses of thyroid medication
What the individual case reports reveal beyond group averages
Why this study remains a milestone for Hashimoto’s research today
Practical takeaways for using AIP to support Hashimoto’s now
Resources:
Abbott Pilot Study (2019): Efficacy of the Autoimmune Protocol Diet as a Part of a Multidisciplinary Supported Lifestyle Intervention for Hashimoto’s Thyroiditis
AIP Foundation Series – Free 5-day email course with printable food lists, meal plans, and beginner guides.