The Dr. Gabrielle Lyon Show

• Comfort is Destroying Your Health: Why Stress is Not the Enemy | Jeff Krasno

  Jeff Krasno’s personal health transformation—reversing diabetes, shedding 60 pounds, and reclaiming his health at age 50—is a masterclass in what he calls “good stress.” In this episode, we dive into the simple but powerful idea that discomfort might just be the medicine we all need. Jeff, the founder of Commune and host of the Commune podcast, shares how fasting, cold exposure, resistance training, and attention to modern habits helped him regain his energy, build muscle, and thrive.Together, we discuss how metabolic dysfunction has become the norm, how adaptive stress responses can be harnessed to reverse chronic illness, and why building muscle is not only the antidote to obesity but also a critical factor in longevity. If you’re interested in reclaiming your vitality and learning how to work with—not against—your biology, this episode will speak to you.We cover:Jeff’s story of personal health transformation at midlifeWhat “good stress” is and how to harness it to improve healthWhy chronic ease leads to chronic diseaseCold therapy, fasting, and training as adaptive stressorsThe importance of resistance training for blood sugar controlHow metabolic dysfunction hides in plain sightPractical tips to increase non-exercise activity thermogenesis (NEAT)Building muscle as the path to longevity and disease preventionWho is Jeff Krasno?Jeff Krasno is the co-founder and CEO of Commune, a masterclass platform for personal and societal well-being. He hosts the Commune podcast, where he’s interviewed luminaries like Deepak Chopra, Gabor Maté, and Matthew McConaughey. Jeff also writes a weekly personal essay called “Commusings,” delivered to over a million subscribers every Sunday. His new project, Good Stress, is an online course, upcoming book, and developing TV series, built on the wellness strategies that helped him reclaim his health after a diabetes diagnosis. He is also the co-creator of the global wellness event series Wanderlust and was selected for Oprah’s SuperSoul100 in 2016.This episode is brought to you by:Puori – Code DRLYON for 20% off sitewide! – https://Puori.com/DRLYONARMRA – Code DRLYON for 15% off! – https://armra.com/DRLYONBON CHARGE – Code DRLYON for 15% off! – https://boncharge.com/DRLYONMUD\WTR – Code DRLYON for up to 43% off – http://mudwtr.com/DRLYONFind Jeff Krasno at:Website – https://www.jeffkrasno.comInstagram – https://www.instagram.com/jeffkrasnoLinkedIn – https://www.linkedin.com/in/jeffkrasnoYouTube – https://www.youtube.com/@CommuneGood Stress (Course & Book) – https://www.goodstress.comFind me at:Instagram: @drgabriellelyonTikTok: @drgabriellelyonFacebook:

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  1:46:37
• Steroids & Testosterone: The Science Behind Anabolic Therapies | Nelson Vergel

  Nelson Vergel’s story is one of resilience, perseverance, and an unrelenting drive to defy the odds. In the mid-1980s, he was handed what many would have considered a death sentence—an HIV diagnosis at a time when there were no effective treatments, no clear answers, and little hope. Today, he is a beacon of knowledge and empowerment for those seeking to take control of their health, whether they are dealing with wasting conditions, hormone deficiencies, or simply aiming for peak performance. Nelson has spent decades researching and advocating for hormone health, muscle preservation, and medical autonomy, particularly for those facing wasting conditions like HIV and cancer. His work has helped shape the conversation around androgen therapies, the role of anabolic agents in aging, and the intersection of GLP-1 medications with muscle loss.We cover:Nelson's personal journey from an HIV diagnosis to hormone optimizationThe history, misconceptions and stigma surrounding anabolic agentsThe differences between various anabolic agents and how they work The impact of GLP-1 medications on lean mass and how to mitigate muscle lossBest practices for hormone monitoring and optimizationIf you want to hear an inspiring story of overcoming the odds to take control of your own health or you’re curious about anabolic therapies and longevity, you can’t miss this one. Who is Nelson Vergel?Nelson Vergel is a chemical engineer, author, and health advocate who has made significant contributions to men's health and hormone optimization. His most recent book, Beyond Testosterone, provides a detailed color guide to educate clinicians and patients about the latest advances in the use of testosterone, anabolics, and other therapies to maximize health and productivity.This episode is brought to you by:LMNT - Code DRLYON for a free LMNT Sample Pack! – http://drinklmnt.com/drlyoOur Place - Code DRLYON for 10% off – https://fromourplace.comTimeline - Code DRLYON for 10% OFF – https://timelinenutrition.com/DRLYONOneSkin - Code DRLYON for 15% off! – https://www.oneskin.co/Find Nelson Vergel at:DiscountedLabs.com – Offers affordable blood tests for monitoring hormones and overall health. ExcelMale.com – A leading 14-year forum with over 42,000 members discussing TRT, hormone health, supplements, and fitness. TRT Facebook Group - https://www.facebook.com/groups/testosteronereplacementWomen’s Healthand HRT Group - https://www.facebook.com/groups/womenHRT LinkedIn - https://www.linkedin.com/in/nvergel/Amazon –

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  1:35:42
• The Truth About Calories and Weight Loss | Dr. James Hill

  Dr. James Hill—a expert on obesity, metabolism, and long-term weight management—joins me this week to unpack the biggest challenges in sustainable fat loss. Dr. Hill has spent decades researching weight control and the factors that determine whether people can keep weight off long-term. We discuss the science behind energy balance, metabolic flexibility, and why long-term weight loss is about more than just diet and exercise. He shares insights from his groundbreaking work with the National Weight Control Registry, the role of GLP-1 medications, and why physical activity is the key to preventing weight regain.We cover:The critical differences between weight loss and weight maintenanceWhy physical activity is perhaps more important for keeping weight off than losing itThe National Weight Control Registry: lessons from long-term weight loss success storiesHow metabolism, muscle mass, and energy expenditure affect weight regainThe role of protein and resistance training in preserving lean massThe impact of GLP-1 medications on weight loss and why most people regain weight after stopping themThe psychology of weight maintenance: mindset, self-monitoring, and behavior changeIf you’ve ever struggled to keep weight off, or you’re interested in the latest research on metabolic health and sustainable weight management, this episode is a must-listen.Who is Dr. James Hill?Dr. James Hill is an internationally recognized expert on obesity, metabolism, and weight management. He is the co-founder of the National Weight Control Registry, the largest ongoing study tracking individuals who have successfully lost weight and kept it off long-term. Dr. Hill has published over 400 scientific articles and has led pioneering research on energy balance, metabolic flexibility, and the role of physical activity in weight maintenance. He is a professor at the University of Alabama at Birmingham and has served as the President of The Obesity Society. His work has been instrumental in shaping modern obesity treatment and prevention strategies.This episode is brought to you by: Puori - Code DRLYON for 20% off sitewide!– https://Puori.com/DRLYON Cozy Earth - Code DRLYON for up to 40% off! – https://cozyearth.com/DRLYON BON CHARGE - Code DRLYON for 15% off! - https://boncharge.com/DRLYONManukora- Get $25 off the Starter Kit at https://manukora.com/DRLYONFind Dr. James Hill at:International Weight Control Registry https://internationalweightcontrolregistry.org/Scholars Profile - https://scholars.uab.edu/6698-james-hillAcademic Website - https://www.uab.edu/norc/about-us/leadership/executive-committee/james-hillFind me at: Instagram: @drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX: x.com/drgabriellelyonApply to

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  1:40:31
• The Science of Optimizing Your Testosterone | Abraham Morgentaler, MD

  In this episode, Dr. Abraham Morgentaler—an expert in urology and hormone health—helps unpack the biggest myths and misconceptions surrounding testosterone therapy for both men and women. He shares his pioneering research on testosterone replacement therapy, challenging outdated fears about its link to prostate cancer and highlighting the latest findings on how hormone therapy can impact overall health, libido, and longevity. The conversation explores the controversial history of testosterone in medicine, the common mismanagement of hormone deficiencies, and why free testosterone may be one of the most important markers for health.We cover:The truth behind the testosterone-prostate cancer debateHow testosterone deficiency is linked to obesity, cardiovascular disease, and dementiaThe stigma around testosterone therapy and why so many people remain untreatedThe effects of testosterone therapy on fertility, muscle mass, and mental well-beingThe role of testosterone in women's health and agingThe latest advancements in testosterone treatments and how they compareWhether you’re considering testosterone therapy, navigating hormone-related issues, or just interested in optimizing your health, this episode offers critical insights that could reshape your understanding of testosterone and its role in overall well-being.Who is Abraham Morgentaler? Dr. Abraham Morgentaler is a leading expert in men’s health and a pioneer in the treatment of testosterone deficiency. His research helped overturn the long-held belief that testosterone therapy increases prostate cancer risk, and he has published over 200 scientific articles on testosterone, prostate cancer, and male sexual health. A Harvard-trained urologist, he is currently the Blavatnik Faculty Fellow in Health and Longevity at Harvard Medical School. Dr. Morgentaler is also the founder of Men’s Health Boston and co-founder of the Androgen Society, and he continues to educate clinicians worldwide through his virtual fellowship and best-selling books on men's health.This episode is brought to you by: LMNT - Code DRLYON for free LMNT Sample Pack! - http://drinklmnt.com/drlyonOneSkin - Code DRLYON for Get 15% off! - https://www.oneskin.co/ Timeline - Code DRLYON for 10% OFF - https://timelinenutrition.com/DRLYONNeeded - Code DRLYON 20% off your first order - https://thisisneeded.comFind Dr. Morgentaler at: T4L Education: https://t4leducation.com/Linked In: https://www.linkedin.com/in/abraham-morgentaler-md-81628b6/ YouTube:

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  1:54:29
• The Truth About Nutrition: How You Can Take a Science-Based Approach | Bradley Johnston PhD

  Misinformation in nutrition is rampant. From demonizing red meat to hyping plant-based diets, conflicting advice has left many people confused about what’s truly evidence-based. In this episode, I am joined by Dr. Bradley Johnston, an expert in evidence-based nutrition and public health policies, to separate fact from fiction. With nearly 200 peer-reviewed publications, Dr. Johnston has challenged conventional wisdom—including recommendations from major organizations like the World Health Organization. He shares how evidence-based practices should guide our dietary choices, the importance of systematic reviews and meta-analyses, and how cognitive biases influence the research we trust.Key Points: How evidence-based guidelines are formed—and why they sometimes changeThe three pillars of evidence-based practice and why patient values matterWhy most nutrition studies aren’t as strong as we think—and how to critically evaluate themWhat the best available research actually says about dietary patterns for longevityThe role of AI in research and whether it’s a help or hindrance to scientific rigorIf you’ve ever questioned dietary guidelines, nutrition headlines, or conflicting health advice, this episode is a must-listen. Get ready to rethink everything you thought you knew about nutrition.Who is Dr. Bradley Johnston? Dr. Bradley Johnston is an Associate Professor at Texas A&M University, specializing in evidence-based nutrition, and the methodology of patient-reported outcomes, randomized clinical trials, systematic reviews, and clinical and public health practice guidelines. With a PhD in experimental medicine from the University of Alberta and post-doctoral training in evidence-based practice, epidemiology and biostatistics from Oxford and McMaster University, his research focuses on advancing human health research methodology to improve clinical and dietary practice recommendations and public health policies. He co-leads EvidenceBasedNutrition.org and NutriRECS, develops nutrition education resources (e.g. Nutrition Users’ Guides), and currently serves as Co-Chair of the Canadian Pediatric Obesity Management Guidelines, ensuring clinical and public health guidelines are backed and transparently supported by the best available evidence, including end user values and preferences, absolute estimates of effect and the certainty of evidence for estimates of effect. His overall aim is to empower patients, clients and members of the public to make fully-informed health care decisions based on the central tenets of evidence-based practice and policy. This episode is brought to you by: Timeline -Code DRLYON for 10% OFF https://timelinenutrition.com/DRLYONPuori - Code DRLYON for 20% OFF - https://puori.com/DRLYONBonCharge - Code DRLYON for 15% OFF - https://boncharge.com/DRLYONARMRA - Code DRLYON for 15% off! - https://armra.com/DRLYON/Find Dr. Bradley Johnston at: Evidence Based Nutrition - https://www.evidencebasednutrition.orgNutrition Users' Guides -https://www.evidencebasednutrition.org/nutrition-user-guidesTexas A&M University -

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  1:30:53

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